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Updated: Aug 18, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)

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对人类淋巴毒素的cDNA的克隆和表达,一种具有瘤坏死活性的淋巴毒素

P W Gray, B B Aggarwal, C V Benton

    Nature
    |December 20, 1984
    PubMed
    概括

    研究人员设计了一种合成的基因,用于E. coli中人类淋巴毒素的表达. 由此产生的复合淋巴毒素在体外和体内瘤缩中显示出显著的瘤细胞细胞毒性.

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    Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
    Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...