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Updated: Jul 10, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

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Published on: February 3, 2013

通过在其可变区域中的单个氨基酸替代,防止兰巴达2免疫球蛋白链的分泌

G E Wu, N Hozumi, H Murialdo

    Cell
    |May 1, 1983
    PubMed
    概括

    兰巴达2光链中的单个氨基酸从甘氨酸转变为氨酸,可以防止其分泌. 在免疫球蛋白A (IgA) 髓瘤细胞的可变区域中,这种糖氨酸替代氨酸会影响蛋白质出口.

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