相关实验视频

Updated: Jul 25, 2026

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
11:21

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

Published on: September 10, 2017

确定人类T细胞受体β链的多样性部分,并与类似的小鼠元素进行比较

S P Clark, Y Yoshikai, S Taylor

    Nature
    |September 3, 1984
    PubMed
    概括

    研究人员在T细胞受体β链基因组合中发现了一种新的多样性元素 (Dβ1.1). 这一发现揭示了适应性免疫和抗原识别背后的复杂遗传机制.

    更多相关视频

    Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin11:17

    Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

    Published on: March 10, 2021

    T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing08:59

    T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing

    Published on: January 12, 2021

    相关概念视频

    Diversity of Antigen Receptors01:28

    Diversity of Antigen Receptors

    Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
    Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
    T Cell Activation and Clonal Selection01:22

    T Cell Activation and Clonal Selection

    T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
    Naive T cells that have not yet encountered an antigen express two primary CD...