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Updated: Aug 1, 2026

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

人类T细胞受体α链的主要结构

G K Sim, J Yagüe, J Nelson

    Nature
    |December 20, 1984
    PubMed
    概括

    研究人员确定了T细胞受体α链的cDNA克隆,揭示了它的结构和基因重排. 这一发现促进了对T细胞识别及其与免疫球蛋白的联系的理解.

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    Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs11:21

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    Protein Organization01:13

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    Antibody Structure

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    Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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    Protein Organization01:24

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    Protein Organization01:24

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    Diversity of Antigen Receptors01:28

    Diversity of Antigen Receptors

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