脂质研究诊所 超脂血和低脂血的程序参考值
JAMA
|October 14, 1983
概括
北美人口中胆固醇和甘油三的新参考值可能会导致更多的年轻人被诊断为高胆固醇血症,更少的成年人被诊断为高甘油三血症.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 临床生物化学 临床生物化学
背景情况:
- 确定的血脂分布对于诊断脂质不良症至关重要.
- 以前的参考值可能不准确地反映了当前人口的健康状况.
- 北美人口表现出多样化的脂质特征.
研究的目的:
- 为了确定血脂的新年龄和性别特定的参考值.
- 评估新参考值对超脂血症和低脂血症诊断的影响.
- 为人口查脂质疾病提供更新的指南.
主要方法:
- 血胆固醇和甘油三分布的分析在北美十个人口中的60,502名参与者中.
- 在7055名白人参与者的随机样本中测量脂蛋白胆固醇水平.
- 根据收集的数据,选择新的特定年龄和性别的参考值.
主要成果:
- 确定了诊断超脂血症和低脂血症的新参考值.
- 实施这些值将增加年轻人的高胆固醇血症诊断.
- 预计成年人中高甘油三血症诊断的显著减少.
结论:
- 更新的参考值对于准确的失脂症诊断至关重要.
- 拟议的参考值将改变基于人口的查结果.
- 这些发现需要重新评估当前高脂血症和高甘油三血症诊断标准.
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