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Updated: Aug 13, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
15:07

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

Published on: December 28, 2015

人体免疫球蛋白可变区域基因 - - 两个V kappa基因和一个伪基因的DNA序列

D L Bentley, T H Rabbitts

    Nature
    |December 25, 1980
    PubMed
    概括

    研究人员对人类的卡帕可变区域 (V kappa) 基因进行了测序,揭示了人类和小鼠V kappa基因之间的高度同质性. 这表明在淋巴细胞中免疫球蛋白基因重组的保存机制.

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