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相关概念视频

Genetic Lingo01:11

Genetic Lingo

Overview
Pedigree Analysis01:35

Pedigree Analysis

Overview
Pedigree Analysis01:35

Pedigree Analysis

Overview
X and Y Chromosomes02:32

X and Y Chromosomes

Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...

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相关实验视频

Updated: Jun 8, 2026

RiboTag Immunoprecipitation in the Germ Cells of the Male Mouse
10:00

RiboTag Immunoprecipitation in the Germ Cells of the Male Mouse

Published on: March 4, 2020

衰退的男性决定性基因.

S S Wachtel, P Basrur, G C Koo

    Cell
    |September 1, 1978
    PubMed
    概括

    在山羊中被调查的基因 (P) 导致无角性,并且可以导致XX雌性中跨性别的发展. 这表明P在性别决定中的作用是衰退的,可能涉及Y染色体基因.

    科学领域:

    • 遗传学 是一个遗传学.
    • 生殖生物学 生殖生物学
    • 动物科学动物科学

    背景情况:

    • 众所周知,山羊的自体主导受访基因 (P) 导致无角性.
    • 染色体女性 (XX) 的同卵性P/P状况导致丸或卵子的发育,表明在性别确定中发挥了作用.

    研究的目的:

    • 研究受访基因 (P) 在山羊的性别决定中的作用.
    • 了解山羊中调查的跨性别状况的遗传基础.

    主要方法:

    • 对山羊无角性和跨性别的遗传基础的分析.
    • 在受访的跨性别山羊中检查H-Y抗原的表达.

    主要成果:

    • 被调查的基因 (P) 在其丸决定性特性中充当了自体逆向的作用.
    • 被调查的跨性别山羊 (XX) 是H-Y阳性,表明与Y染色体相关的基因有联系.
    • 这些发现支持Y染色体上转移丸决定基因的假设.

    结论:

    • 被调查的基因 (P) 或与之密切相关的基因在山羊的性别决定中起着衰退作用.
    • 从Y染色体转移丸决定的H-Y基因可能解释了在受访的跨性别山羊中观察到的衰退性性别决定.

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    Last Updated: Jun 8, 2026

    RiboTag Immunoprecipitation in the Germ Cells of the Male Mouse
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    Published on: March 4, 2020

    CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis
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    Screening Sperm for the Rapid Isolation of Germline Edits in Zebrafish

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