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相关概念视频

Immunological Memory01:23

Immunological Memory

14.9K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
14.9K
Development of Immunocompetence01:22

Development of Immunocompetence

769
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
769
Rh Blood Group01:19

Rh Blood Group

2.7K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
2.7K
Active versus Passive Immunity01:31

Active versus Passive Immunity

9.9K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
9.9K
Vaccinations01:51

Vaccinations

51.1K
Overview
51.1K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

8.4K
The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
8.4K

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相关实验视频

免疫接种后红疹抗体的持久性

K L Herrmann, S B Halstead, N H Wiebenga

    JAMA
    |January 8, 1982
    PubMed
    概括
    此摘要是机器生成的。

    这项研究追踪了十年的红疹病毒疫苗免疫力. 结果显示,在超过97%的接种疫苗的人群中,抗体持续性高,免疫力稳定.

    相关实验视频

    科学领域:

    • 病毒学 病毒学
    • 免疫学 免疫学 免疫学
    • 公共卫生 公共卫生

    背景情况:

    • 红疹病毒是一个重大的公共卫生问题.
    • 活体,减弱的红疹病毒疫苗对于预防疾病至关重要.
    • 评估疫苗诱导的长期免疫力对于公共卫生战略至关重要.

    研究的目的:

    • 为了评估三种活体,减弱的红疹病毒疫苗诱导的免疫的持久性.
    • 为了评估疫苗接种后的长期血清学反应.
    • 为了确定血液凝结抑制 (HI) 抗体标位在十年内持续的持续性.

    主要方法:

    • 一项涉及三种红疹病毒疫苗的比较实地试验:Cendehill,HPV 77 DE-5和HPV-77 DK-12.
    • 开始于1969年,首次进行血清转化评估.
    • 定期血清学测试 (HI标位) 在接种疫苗的队列上进行了十年的时间.

    主要成果:

    • 所有疫苗组的初始血清转化率都超过了98%.
    • 平均HI标位在前四年下降了约50%,然后稳定下来.
    • 在4年至10年间,抗体水平保持稳定,每年回归到低位数的回归率不到0.5%.
    • 超过97%的接种疫苗的人在整个十年的研究期间保持了可测量的HI抗体水平.

    结论:

    • 活体,减弱的红疹病毒疫苗诱导高初始血清转化率.
    • 有效的红疹疫苗,当正确使用时,提供持久的,长期的免疫力.
    • 抗体持久率高支持红疹疫苗的长期疗效.