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Updated: May 11, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization

Published on: February 3, 2013

在老鼠的T/t复合体内基因映射. II. II. II. II. II. II. II. II. II. II. II. II. II. II. II. II. II. II. 在t个单元型中,H-2复合体的异常位置

K Artzt, H S Shin, D Bennett

    Cell
    |March 1, 1982
    PubMed
    概括

    17号染色体上的T单元类型抑制了基因重组,影响了H-2复合体的进化. 这些链接基因,作为超基因复合体遗传,由于雄性传播率高,在野生小鼠中很普遍.

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    Position-effect Variegation02:32

    Position-effect Variegation

    In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.