概括
在冠状动脉绑定后,使用二维回声心脏图评估了区域左心室功能. 异常收缩的细分 (ACS) 过度预测了早期的心脏病发作的大小,突出了追踪心脏病发作过程的需要,而不是预测大小.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 心肌梗塞研究研究
背景情况:
- 评估区域左心室功能对于了解心肌梗塞至关重要.
- 二维回声心脏图 (2D回声) 提供了定量区域心肌缩数据.
- 建立正常的加厚模式对于识别功能障碍至关重要.
研究的目的:
- 在狗冠状动脉绑定后,使用二维回声对区域左心室功能进行序列评估.
- 为了将心肌功能障碍的心声学评估与实际心脏病发作大小进行比较.
- 确定异常收缩细分 (ACS) 在预测心脏病发作大小 (IS) 中的实用性.
主要方法:
- 20只狗接受了左前下垂冠状动脉绑定.
- 量化二维回声被用于评估区域性心肌厚化.
- 20只健康狗的正常值作为对照.
- 心脏病发作大小在48小时后被确定,并与ACS预测在2,24和48小时后进行比较.
主要成果:
- 正常的心脏表现出一致的,虽然可变的,心肌缩.
- 在合后,心肌段 either either 稀疏或未能加厚.
- 异常收缩部分 (ACS) 在2小时内预测过度预测了心脏病发作大小 (IS) (25.3%对13.4%).
- 在48小时后,ACS对IS的预测有所改善,但相关性仍然很公平 (r=0.73).
- 心肌功能障碍在2小时后往往超过了以后的评估.
结论:
- 显著的异质性存在于通过二维回声对心肌厚度的测量.
- 在健康的犬类心脏中,心肌缩的失败并不存在.
- 早期的ACS高估了心脏病发作的大小,这表明ACS更好地跟踪心脏病发作的进展,而不是预测最终的大小.
相关概念视频
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