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Updated: May 31, 2026

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
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Published on: August 13, 2013

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被禽类红细胞母细胞瘤病毒感染的细胞分化并转化为转化细胞

J Samarut, L Gazzolo

    Cell
    |April 1, 1982
    PubMed
    概括

    鸟类红细胞母细胞病毒 (AEV) 转化早期的红色素原生细胞. 这些转变的细胞表现出后来的红色素原体的特征,表明在殖民地形成单位-红色素 (CFU-E) 阶段存在分化阻断.

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    相关概念视频

    Forced Transdifferentiation01:28

    Forced Transdifferentiation

    Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
    Artificial transdifferentiation occurs...