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Updated: Aug 11, 2026

Production of Genetically Engineered Golden Syrian Hamsters by Pronuclear Injection of the CRISPR/Cas9 Complex
06:12

Production of Genetically Engineered Golden Syrian Hamsters by Pronuclear Injection of the CRISPR/Cas9 Complex

Published on: January 9, 2018

从横向传播的叙利亚仓鼠淋巴瘤中分离的不寻常的可过致癌剂

J H Coggin, J E Oakes, R J Huebner

    Nature
    |March 26, 1981
    PubMed
    概括

    一种传染病原体,可能是病毒,在子中引起恶性淋巴瘤. 这种无细胞剂被分离出来,在注射后成功诱导淋巴瘤,证实了它的传染性.

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    An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis06:38

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    Rous Sarcoma Virus (RSV) and Cancer01:03

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    Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
    RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...