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Updated: Jul 13, 2026

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System
08:48

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System

Published on: December 21, 2016

与双分钟染色体相关的改变的二叶酸减少酶基因的不稳定放大

D A Haber, R T Schimke

    Cell
    |November 1, 1981
    PubMed
    概括

    鼠标纤维细胞通过基因放大和突变而发展出甲状腺素耐药性. 在染色体外元素上选择了带有改变二叶酸还原酶基因的变异细胞,证明了基因放大和染色体动态.

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