直流反冲击对心肌区域收缩性和 perfusion 的影响. 实验研究实验研究
Circulation
|February 1, 1981
概括
高能量的电反冲击可以损害心脏肌肉. 皮心冲击影响了收缩能力,但高达460 J的胸前冲击对狗的心肌功能或输液没有影响.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏外科手术 心脏外科手术
背景情况:
- 电力反冲击用于治疗心律失常症.
- 高能量冲击可能会导致心肌损伤,但功能相关性尚未得到充分理解.
研究的目的:
- 研究电反冲击对心肌收缩和 perfusion 的功能影响.
- 为了区分心上冲击和胸前冲击的影响.
主要方法:
- 声微波测量用于测量45只狗的心肌收缩率.
- 放射标记的微球评估了心肌输液.
- 对跳动和动的心脏进行了直接 (表心) 和胸前冲击.
主要成果:
- 高能量的或重复的心上震动导致心下收缩异常,表明功能损伤.
- 单次或多次的胸前冲击 (高达460J) 并没有导致可检测的收缩异常.
- 心肌输液没有受到任何测试的冲击的影响.
结论:
- 在高能量和度下输送的电流可以功能性地损害心肌.
- 在开放式胸部除时,建议使用初始的低能量 (10-20 J).
- 高能量的胸前冲击似乎对正常的心肌收缩和输液安全.
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