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Updated: May 12, 2026

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease
15:23

Selection of Aptamers for Amyloid β-Protein, the Causative Agent of Alzheimer's Disease

Published on: May 14, 2010

与LDL受体相关的蛋白质,多功能ApoE受体,结合分泌的β-粉样蛋白前体蛋白并调解其降解

M Z Kounnas1, R D Moir, G W Rebeck

  • 1Department of Biochemistry, Holland Laboratories, American Red Cross, Rockville, Maryland 20855, USA.

Cell
|July 28, 1995
PubMed
概括

低密度脂蛋白 (LDL) 受体相关蛋白 (LRP) 中介于分泌的β-粉样蛋白前体蛋白 (APP) 的细胞吸收和降解. 这一发现将LRP和APP代谢与阿尔茨海默病 (AD) 风险因素联系起来.

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Imaging the Intracellular Trafficking of APP with Photoactivatable GFP

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