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Updated: Sep 3, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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通过TNF受体2和CD40通过TRAF2-介导的NF-kappa B的激活

M Rothe1, V Sarma, V M Dixit

  • 1Molecular Biology Department, Tularik, Inc., South San Francisco, CA 94080, USA.

Science (New York, N.Y.)
|September 8, 1995
PubMed
概括

瘤亡因子受体相关因子2 (TRAF2) 调解TNF-R2和CD40通路的信号传递. 过度表达TRAF2会激活NF-kappa B,而TRAF2衍生物会抑制这种激活.

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