补充剂对妊娠结果的影响
R L Goldenberg1, T Tamura, Y Neggers
1Department of Obstetrics and Gynecology, University of Alabama at Birmingham 35233-7333, USA.
JAMA
|August 9, 1995
概括
怀孕期间补充显著增加了婴儿的出生体重和头周长. 这种效应在体重指数低于26公斤/平方米的女性中最为明显,这表明有针对性的益处.
科学领域:
- 孕产妇和胎儿健康 孕产妇和胎儿健康
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 孕产妇的营养显著影响胎儿发育和出生结果.
- 是一种重要的微量营养素,对胎儿的生长和发育至关重要.
- 低母体水平与不良妊娠结果有关.
研究的目的:
- 调查怀孕期间补充剂与婴儿出生体重之间的关联.
- 评估对其他新生儿人体测量的影响,例如头周长.
- 探索母体体重指数对影响的潜在缓解作用.
主要方法:
- 一个随机,双盲,安慰剂对照试验,涉及580名孕妇.
- 参与者是医疗贫困,健康的非裔美国女性,血含量低于中位数.
- 干预包括每天25毫克或安慰剂,从怀孕19周到分娩.
主要成果:
- 补充剂导致婴儿出生体重 (126克) 和头周长 (0.4厘米) 显著增加.
- 在体重指数<26公斤/米2的女性中,增加了248克的出生体重和0.7厘米的头周.
- 在补充剂的组中观察到更高的血度.
结论:
- 在怀孕早期每天补充与婴儿出生体重和头周长的改善有关.
- 的有益作用在体重指数低于26公斤/米2的孕妇中更为明显.
- 补充剂可能是一个有价值的策略,以提高风险人群的胎儿生长.
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