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Updated: Aug 13, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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3849+10 kb C-->T突变和囊性纤维化中的疾病严重程度

R C Stern1, C F Doershuk, M L Drumm

  • 1Leroy W Matthews Cystic Fibrosis Center, Department of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.

Lancet (London, England)
|July 29, 1995
PubMed
概括

囊性纤维化 (CF) 患者具有3849 + 10kB的C->T结合突变,表现出不同的疾病严重程度. 这种突变可能导致不太严重的胰腺和延迟的肺部问题,但生殖道疾病可能会进展.

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