肺循环中的内血管支架. 对管理和中期随访的临床影响

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Updated: Aug 19, 2026

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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

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R Fogelman¹, D Nykanen, J F Smallhorn

¹University of Toronto, Faculty of Medicine, Department of Pediatrics, Ontario, Canada.

Circulation

|August 15, 1995

概括

内血管支架有效治疗肺动脉狭窄症,改善患者的治疗结果. 然而,可以发生内阻塞,需要长期监测和肺动脉狭窄管理的潜在重新干预.

科学领域:

心脏病学心脏病学
干预性放射学干预性放射学
儿童心脏病学儿童心脏病学

背景情况:

肺动脉狭窄 (PAS) 是一种复杂的疾病,通常需要干预.
内血管支架为非气球可扩展PAS提供了一种有前途的方法.
在PAS中支架的长期疗效和潜在并发症需要进一步定义.

研究的目的:

评估肺动脉狭窄症患者内血管支架植入的临床结果.
评估支架结合的模式和植入后复原的发展.
确定支架在缓解狭窄和改善患者症状方面的影响.

主要方法:

对42名患者 (年龄为6.1±4.7岁) 的前性随访,这些患者接受了55个气球可扩展支架.
植入后1年进行了再导管,以评估支架的整合和光线狭窄.
评估直径增加,梯度减少和临床结果,包括避免手术.

主要成果:

术后观察到显著的直径增加 (109 ± 79%) 和梯度减少 (74 ± 26%).
在重新导管时,所有患者都出现了内狭窄,特别是在直径不匹配的区域.
在大多数患者中,穿皮支架成功避免或推迟了计划中的手术,在27名患者中报告了症状改善.

结论:

内血管支架在控制肺动脉狭窄方面发挥着重要作用,对临床护理产生积极影响.
狭窄症的缓解可以通过内支架阻塞受到限制,需要潜在的再扩展 (15/55支架).
对于患者进行支架植入为肺动脉狭窄的患者,长期随访至关重要.

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