骨质疏松透析骨质疏松症:有证据表明一种由水传播的病因因因子,可能是
Lancet (London, England)
|April 22, 1978
概括
使用脱离离子水进行透析可显著减少患者的骨质疏松症和透析脑病变. 这与血清含量降低有关,这表明水中的是关键因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床化学 临床化学
背景情况:
- 骨质疏松症和透析脑病是影响定期血液透析患者的严重疾病.
- 这两种情况都在透析中心观察到,自来水中含量很高.
研究的目的:
- 研究水的纯度对血液透析患者骨质疏松症的发展的影响.
- 探索含量,水处理和骨质疏松症和透析脑病变的发生率之间的关系.
主要方法:
- 在使用脱离离子水与软化水用于透析制备的患者中,骨质疏松症的患病率的比较.
- 在接受定期血液透析的患者中测量血清度.
- 水供应,血清和临床结果 (骨质疏松症,脑病变) 之间的相关性分析.
主要成果:
- 与使用软化水 (70%) 的患者相比,在用脱离离子水进行透析的患者中,骨髓显著较少 (15%).
- 使用软化水的患者表现出比使用脱离离子水的患者更高的血清度.
- 在透析脑病和痴呆症患者中发现血清含量升高,尽管在治疗时间较长的无症状患者中观察到类似的水平.
结论:
- 在血液透析中使用脱离离子水可以大大降低骨质疏松症的发生率.
- 从透析剂中吸收被强烈认为是骨质疏松症和透析脑病变的原因.
- 在自来水中含量高的地区,水处理以去除 (脱离离子,反透) 是合理的.
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