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Updated: Aug 14, 2026

Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis (EAE) Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
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转基因小鼠表达一种髓基蛋白特异性T细胞受体,会发展自发的自身免疫力

J Goverman1, A Woods, L Larson

  • 1Division of Biology, California Institute of Technology, Pasadena 91125.

Cell
|February 26, 1993
PubMed
概括

研究人员创造了一种针对多发性硬化症 (MS) 的新老鼠模型,该模型自发地发展出该疾病. 这种模型有助于研究导致MS等自身免疫性疾病的遗传和环境因素.

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