相关实验视频

Updated: Aug 19, 2026

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)

Published on: April 21, 2019

在儿童过敏中IgG4亚类的作用

C M Gwynn, J M Smith, G L Leon

    Lancet (London, England)
    |April 29, 1978
    PubMed
    概括

    喘患者免疫球蛋白E (IgE) 和IgG4水平升高与临床严重程度相关. 高的IgG4表明对二染糖酸盐的反应不佳,而高的IgE则表明反应良好.

    更多相关视频

    Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System10:25

    Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System

    Published on: September 20, 2019

    Humanized Mediator Release Assay as a Read-Out for Allergen Potency10:22

    Humanized Mediator Release Assay as a Read-Out for Allergen Potency

    Published on: June 29, 2021

    相关概念视频

    Antibody Structure01:10

    Antibody Structure

    Overview
    Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
    The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
    Antibodies consist of four polypeptide chains: two identical heavy...
    Allergic Reactions02:06

    Allergic Reactions

    Overview
    Allergic Drug Reactions01:27

    Allergic Drug Reactions

    Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
    Development of Immunocompetence01:22

    Development of Immunocompetence

    The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
    The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
    Subsequent T...
    Hypersensitivities01:30

    Hypersensitivities

    Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
    Types of Hypersensitivities
    Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
    Hypersensitivity Reactions: Delayed Hypersensitivity Reactions01:29

    Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

    Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...