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Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
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在B细胞中诱导人类IgE合成,由巨细胞和基细胞诱导

J F Gauchat1, S Henchoz, G Mazzei

  • 1Glaxo Institute for Molecular Biology, Geneva, Switzerland.

Nature
|September 23, 1993
PubMed
概括

乳腺细胞和基细胞是过敏的关键参与者,可以直接调节免疫球蛋白E (IgE) 的产生. 这些细胞表达CD40连接体 (CD40L),它刺激IgE合成,这表明,除了释放炎症媒介之外,还有一个新的作用.

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