人类 uracil-DNA glycosylase 的晶体结构和突变分析:特异性和催化作用的结构基础

C D Mol1, A S Arvai, G Slupphaug

  • 1Department of Molecular Biology, Scripps Research Institute, La Jolla, California 92037.

Cell
|March 24, 1995
PubMed
概括

人类 uracil-DNA glycosylase (UDG) 晶体结构揭示了它如何特别识别和结合 uracil. 这种DNA修复酶使用预制的口袋和键来确保准确的损坏基的识别.

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