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Updated: Aug 8, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
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Published on: April 16, 2015

在缺乏白细胞介素-2受体β的小鼠中放松T细胞激活和自身免疫

H Suzuki1, T M Kündig, C Furlonger

  • 1Amgen Institute, Toronto, Ontario, Canada.

Science (New York, N.Y.)
|June 9, 1995
PubMed
概括

在小鼠中,介质素-2受体β (IL-2Rβ) 缺乏导致T细胞激活,导致B细胞枯竭,自身免疫和早期死亡. IL-2Rβ对于控制T细胞激活和维持免疫平衡至关重要.

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