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Updated: Aug 7, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
14:23

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Published on: August 31, 2014

在HIV-1感染中,抗原振荡和转移免疫优势

M A Nowak1, R M May, R E Phillips

  • 1Department of Zoology, University of Oxford, UK.

Nature
|June 15, 1995
PubMed
概括

细胞毒性T淋巴细胞 (CTL) 通常只识别病原体上的少数表位,这种现象称为免疫主导. 数学建模揭示了病原体变异如何影响CTL反应,影响病毒持久性和疫苗设计策略.

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