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在SH3域中,结定向和序列特异性的结构决定因素

W A Lim1, F M Richards, R O Fox

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114.

Nature
|November 24, 1994
PubMed
概括

SEM-5蛋白质的Src-homology-3 (SH3) 域以一种新的方向与Sos结合,与之前观察到的模式相反. 这种双模式结合机制对于涉及SH3域的通路中的信号特异性至关重要.

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