在子皮层中神经元相互作用的动力学与行为事件的关系
E Vaadia1, I Haalman, M Abeles
1Department of Physiology, Hadassah School of Medicine, Hebrew University, Jerusalem, Israel.
Nature
|February 9, 1995
概括
大脑中的神经发射相关性.
科学领域:
- 神经科学是一个神经科学.
- 计算神经科学是一种神经科学.
- 系统神经科学 系统神经科学
背景情况:
- 皮层功能可能涉及神经元发射同步的动态调制.
- 经过刺激或在行为过程中观察到神经元发射的相关性,但它们与行为相对的时间动态尚不清楚.
研究的目的:
- 系统地评估与行为事件有关的神经元发射相关性修改的时间过程.
- 研究神经元发射相关性动态如何受到神经元距离和发射速率调节的影响.
主要方法:
- 同时记录单个神经元活动在子的前皮层.
- 在行为任务中对相关的射击模式的分析.
主要成果:
- 神经元之间的相关发射迅速 (在几分之一秒内) 和系统地与行为事件一起演变.
- 动态相关性模式取决于神经元之间的距离.
- 神经元相关性可以独立于单个神经元发射率的变化而出现.
结论:
- 神经元可以快速形成和分离功能组来执行计算任务.
- 研究结果表明,一个动态网络模型,其中神经元的协会和解离是关键.
- 现有的神经编码模型仅基于发射率可能需要修订,以纳入动态相关性.
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