相关实验视频

Updated: Aug 6, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Published on: October 12, 2018

通过捐赠者的人工授精传播艾滋病毒

M R Araneta¹, L Mascola, A Eller

¹Los Angeles County Department of Health Services, CA.

|March 15, 1995

概括

1986年之前的捐赠人人工授精 (AI) 存在人类免疫缺陷病毒 (HIV) 传播的风险. 7%的接受来自感染者捐赠者的AI的妇女检测出艾滋病毒阳性,突出了回顾性查和患者调查的必要性.

科学领域:

生殖医学生殖医学
传染病流行病学传染病流行病学
公共卫生公共卫生

背景情况:

在广泛的人类免疫缺陷病毒 (HIV) 查之前,捐赠者授精实践带来了风险.
在1986年之前,通过使用受感染供体精子的人工授精 (AI) 传播艾滋病毒的可能性是严重的公共卫生问题.

研究的目的:

调查和记录通过捐赠人人工授精 (AI) 进行的艾滋病毒传染病例,在实施精子捐赠者的常规艾滋病毒查之前进行.
评估在接受人工智能手术的女性中艾滋病毒感染的患病率,这些女性使用来自确定的艾滋病毒阳性捐赠者的精液.

主要方法:

在五家不孕症诊所进行了回顾性回顾性研究.
识别了艾滋病毒感染女性,先前有AI病史,以追踪捐赠者及其接受者.
接受艾滋病毒感染者确定的捐赠者的人工智能治疗的妇女接受了检查.

主要成果:

在同意接受测试的199名女性中,有7名女性 (3.52%) 在从5名确诊的感染艾滋病毒的捐赠者中接受AI后呈艾滋病毒阳性.
五个有风险信息的捐赠者中,有三个人曾经与男性发生过性关系.
通过与常规捐赠者查无关的情况确定了四名感染艾滋病毒的妇女.

结论:

在1986年之前,通过捐赠AI传播艾滋病毒对接受者构成严重风险.
建议的公共卫生政策包括追溯识别受感染的捐赠者和人工智能接受者,特别是在艾滋病流行地区.
建议询问被诊断为艾滋病毒或艾滋病的妇女,而没有确定的风险因素,关于先前的AI程序.

更多相关视频

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Published on: January 31, 2020

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice

Published on: October 6, 2022

相关概念视频

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

In Vitro Fertilization

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...

Transmission of Pathogens

Transmission of Pathogens

Pathogens spread from their reservoirs to susceptible hosts through three main routes: contact transmission, vehicle transmission, and vector transmission. Each route involves distinct mechanisms of transfer.Contact TransmissionThis category includes direct contact, indirect contact, and droplet transmission:Direct contact involves immediate physical interaction between individuals—such as a handshake—which can spread pathogens like Streptococcus pyogenes, the bacterium responsible for...

Amebiasis

Amebiasis

Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...