大学入学前免疫接种要求对麻疹爆发风险的影响
A L Baughman1, W W Williams, W L Atkinson
1National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333.
JAMA
|October 12, 1994
概括
国家强制性的学前免疫要求 (PIRs) 显著减少了大学校园的麻疹疫情. 拥有PIR的学院显示,麻疹病例较少,这凸显了疫苗接种政策对学生健康的重要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 由于人口密度高,麻疹疫情对大学校园构成重大风险.
- 疫苗接种要求是控制机构环境中传染病传播的关键策略.
研究的目的:
- 评估学前免疫要求 (PIRs) 对美国大学和大学麻疹病例发生率的影响.
- 确定与大学校园中麻疹爆发相关的风险因素.
主要方法:
- 一项对880所学院和大学的调查评估了免疫政策和1988-1991年的麻疹爆发数据.
- 国家麻疹监测数据与各县的调查数据合并,以分析麻疹引入风险.
- 使用后勤回归模型来确定PIR和其他风险因素对麻疹爆发的影响.
主要成果:
- 拥有国家授权的PIR的学院报告麻疹爆发的可能性明显低 (调整后的RR=0.30).
- 在有国家监管或两剂麻疹疫苗PIR.的学校中没有发生大规模疫情 (≥10例).
- 住宅学院和4年公共课程面临更高的麻疹广泛传播风险 (≥5例).
结论:
- 研究结果强烈支持大学生强制接种疫苗的政策,以减轻麻疹疫情.
- 要求PIR的州法规对于防止校园中麻疹传播的广泛传播至关重要.
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