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Updated: Aug 18, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

一个GC特有的DNA小沟结合的设计

B H Geierstanger1, M Mrksich, P B Dervan

  • 1Graduate Group in Biophysics, University of California, Berkeley 94720.

Science (New York, N.Y.)
|October 28, 1994
PubMed
概括

研究人员设计了一种合成,专门与富含GC的DNA序列结合,与结合富含AT区域的类似化合物不同. 这一发现促进了对特定序列DNA识别和小沟结合的理解.

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