概括
细胞毒性化疗药物的成本在1972年至1976年间显著增加,尽管癌症发病率稳定. 这些昂贵的癌症治疗方法并不是传统疗法的廉价替代方案.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
背景情况:
- 在1972年至1976年期间,英国的癌症发病率和患者数量保持稳定.
- 大型医院药物预算中,用于细胞毒药物的比例在此期间大幅上升.
研究的目的:
- 分析与癌症治疗中细胞毒药物使用相关的成本上升.
- 与手术和放射治疗相比,评估细胞毒性化疗的经济可行性.
主要方法:
- 对医院药物预算和药物使用数据的回顾性分析.
- 药物成本,患者发病率和治疗方式的比较.
主要成果:
- 细胞毒药物的使用从医院药物总预算的5.1%增加到14%.
- 增加的成本是由于四种特定的昂贵药物的使用量和单位价格增加.
- 尽管成本上升,但细胞毒性化疗并不是手术和放射治疗的节省成本的替代方案.
结论:
- 昂贵的细胞毒药物的使用应仅限于治愈尝试或临床试验.
- 需要进一步的研究,以优化在晚期癌症的息治疗中使用更便宜的细胞毒药物.
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