血25-基维生素D对长期住院老年患者紫外线照射的反应
Lancet (London, England)
|September 23, 1978
概括
低剂量紫外线照射有效增加了老年患者的血25-氧维生素D (25[OH]D) 水平. 这种方法可以防止在阳光照射有限的老年人中缺乏维生素D.
科学领域:
- 老年医学 老年医学
- 皮肤病学 皮肤病学
- 营养科学 营养科学
背景情况:
- 在长期住院老年病房的老年人中,维生素D缺乏是常见的.
- 在住院老年人群中,有限的阳光照射会导致维生素D水平较低.
研究的目的:
- 为了研究不同紫外线 (UV) 照射剂量对血25-氧维生素D (25[OH]D) 水平的影响.
- 确定紫外线照射是否可以使老年患者的维生素D水平正常化.
主要方法:
- 长期住院老年病房的患者暴露于不同剂量的紫外线辐射.
- 测量了血25-氧维生素D (25[OH]D) 水平,以评估反应.
主要成果:
- 紫外线照射显著增加了血中的25...OH) D水平.
- 剂量低于引起红血的剂量足以使25OH) D水平正常化.
结论:
- 在老年患者中,紫外线照射有效增加血25~OH) D.
- 提供受控的紫外线照射可能是一个可行的策略,以防止维生素D缺乏老年人与最小的阳光照射.
相关概念视频
01:35Mutations
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
01:23Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).