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Updated: Jan 17, 2026

CRISPR/Cas9 Technology in Restoring Dystrophin Expression in iPSC-Derived Muscle Progenitors
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阿达林基因的错误突变与自身逆向性肌肉发育不良相关

S L Roberds1, F Leturcq, V Allamand

  • 1Howard Hughes Medical Institute, University of Iowa College of Medicine, Iowa City 52242.

Cell
|August 26, 1994
PubMed
概括

严重的儿童自体衰退性肌肉发育不良症 (SCARMD) 与阿达林缺乏有关. 研究人员将阿达林基因映射到第17号染色体上,确定了在某些家族中可能导致SCARMD的突变.

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