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Updated: Aug 15, 2026

Analysis of Spliceosomal snRNA Localization in Human Hela Cells Using Microinjection
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Analysis of Spliceosomal snRNA Localization in Human Hela Cells Using Microinjection

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在缺乏U1 snRNP的前mRNA拼接反应中,通过SR蛋白补充SR蛋白

J D Crispino1, B J Blencowe, P A Sharp

  • 1Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139.

Science (New York, N.Y.)
|September 23, 1994
PubMed
概括

高度的SR蛋白可以在没有U1小核核核糖核蛋白 (snRNP) 的情况下启动mRNA前剪接. 这一发现揭示了结合体组装的新途径,这对于理解基因表达调节至关重要.

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