在脑血管造影期间的微观气栓塞及其避免策略
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1Division of Clinical Neurosciences, St. George's Hospital Medical School, London, UK.
Lancet (London, England)
|March 27, 1993
概括
脑血管造影期间的气栓塞会导致神经复杂症. 在注射前让对比剂站立,并使用缓慢的盐水冲洗,可以显著减少气栓,提高患者的安全性.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 生物医学工程 生物医学工程
背景情况:
- 大脑血管造影带有神经复杂症的风险.
- 空气栓塞是导致这些并发症的潜在因素.
研究的目的:
- 在脑血管造影期间调查空气栓塞的发生.
- 确定在手术过程中减少气栓塞的方法.
主要方法:
- 在接受脑血管造影的患者中,跨骨多普勒超声波监测了气栓.
- 羊模型被用来进一步研究在对比介质注射期间的空气栓塞.
- 调查了对比介质站立时间和注射速度对气栓塞的影响.
主要成果:
- 在患者和绵羊模型中,在对比剂注射过程中检测到气栓.
- 让对比介质停留10分钟显著减少了气栓塞的持续时间 (p < 0.001).
- 缓慢注射盐水或不太粘的对比剂显著减少了空气栓塞 (p = 0.004).
结论:
- 空气栓塞是脑血管造影期间的一个显著现象.
- 在注射前使用立体对比剂和缓慢的盐水冲洗是减少气栓塞的有效措施.
- 实施这些措施可以减轻与脑血管学相关的神经功能障碍风险.
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