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Updated: Aug 16, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

转录因子CREB中的蛋白激酶A依赖激活剂揭示了CREM抑制剂的新作用

P Brindle1, S Linke, M Montminy

  • 1Clayton Foundation Laboratories for Peptide Biology, Salk Institute, La Jolla, California 92037.

Nature
|August 26, 1993
PubMed
概括

激素信号通过酸化其酶诱导域 (KID) 来激活CREB转录因子. 这种酸化增强了基因转录,即使KID在单独的分子上.

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