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Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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在T细胞受体突变小鼠中自发发育的炎症性肠病

P Mombaerts1, E Mizoguchi, M J Grusby

  • 1Howard Hughes Medical Institute, Department of Biology Massachusetts Institute of Technology Cambridge 02139.

Cell
|October 22, 1993
PubMed
概括

自发性炎症性肠病 (IBD) 发生在基因向免疫缺陷小鼠中,这些小鼠缺乏特定的T细胞成分,但没有B细胞. 这表明免疫系统功能障碍可能会导致人类的IBD.

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