在玉米中, meiotic 染色体配对与一种新的染色体组织有关
R K Dawe1, J W Sedat, D A Agard
1Department of Molecular and Cell Biology, University of California, Berkeley 94720.
Cell
|March 11, 1994
概括
玉米中性染色体在突触之前经历了显著的结构变化,包括姐妹染色体分离和体积增加. 这种prezygotene重组可能有助于在半分裂过程中同类染色体配对.
科学领域:
- 细胞遗传学 细胞遗传学
- 分子生物学分子生物学
- 植物科学 植物科学
背景情况:
- 染色体突触是变过程中的一个关键过程.
- 了解突触中的早期事件是理解遗传重组的关键.
- 玉米提供了优秀的细胞学特征,用于研究介质染色体动力学.
研究的目的:
- 分析玉米染色体突触的早期结构事件.
- 为了描述prezygotene染色体的形态.
- 为了调查prezygotene结构在同质识别中的潜在作用.
主要方法:
- 使用了三维光显微镜.
- 对玉米中性染色体进行了详细的细胞学分析.
主要成果:
- 准zygotene染色体表现出部分姐妹染色体分离和延长的旋 heterochromatin.
- 总染色体体积增加了50%,表面复杂性增加.
- 端粒位点在周围对齐,而近端位点则没有.
- 在zygotene中,染色体体积减少,它们以单纤维的形式出现.
结论:
- 玉米染色体在突触之前经历了戏剧性的结构重组.
- 专门的prezygotene形态可能有助于同质识别.
- 这些发现为介质性染色体配对的机制提供了见解.
相关概念视频
Meiosis I
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by a...
Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...
Crossing Over
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process called synapsis.
In order to...
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process called synapsis.
In order to...
Meiosis I
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Meiosis I
Meiosis is the division of a diploid cell into haploid cells forming sperm and eggs in animals through differentiation. Meiosis I is the first stage of meiosis, where the genetic recombination of homologous chromosomes and the reduction of the ploidy level by half occurs.
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Prophase I is the most extended and complex step of meiosis I characterized by synapsis, chromosome pairing, and recombination of the homologous chromosomes. This process is facilitated by a proteinaceous structure called the...
Crossing Over
Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I, duplicated...


