中枢静脉导管的血栓和感染性并发症之间的关系
1Department of Medical Specialities, University of Texas M. D. Anderson Cancer Center, Houston 77030.
JAMA
|April 6, 1994
概括
在癌症患者中长期使用血管导管经常导致血栓并发症,近一半的导管静脉显示病理变化. 这些血栓事件与导管相关性败血症的发展有显著的关联.
科学领域:
- 在瘤学瘤学.
- 血管外科 血管外科
- 传染性疾病 传染性疾病
背景情况:
- 在癌症患者中,长期使用血管导管是常见的,用于治疗.
- 血管导管可能与严重的并发症有关,包括血栓形成和感染.
研究的目的:
- 确定长期血管导管的癌症患者中血栓和感染性并发症的发生率.
- 为了研究血栓和传染性并发症之间的关系.
主要方法:
- 在第三级癌症中心进行了一系列回顾性病例.
- 在72名癌症患者身上,对导管和逆侧静脉进行了死后检查.
- 收集了与导管相关的败血症和静脉病理变化的数据.
主要成果:
- 在49%的导管静脉和9.2%的对照静脉 (P < .001) 中观察到病理变化.
- 在38%的导管静脉中发现了壁血栓,而对照组的这一比例为1.4% (P < .001).
- 七名患者 (9.7%) 发生了与导管相关的败血症,这与墙壁血栓形成有显著的关联 (P < .01).
结论:
- 血栓并发症在癌症患者的导管静脉中很常见.
- 导管静脉中的血栓形成通常与导管相关的败血症有关.
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