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患高血压的成年人患病率和死亡率,其脚/手臂血压指数较低
A B Newman1, K Sutton-Tyrrell, M T Vogt
1Department of Medicine, Medical College of Pennsylvania, Pittsburgh 15212.
JAMA
|July 28, 1993
概括
脚/手臂血压指数 (AAI) 较低是一个显著的预测器增加心血管风险的老年人患有静脉压高. 这一发现强调了AAI作为心血管事件和死亡率的关键标记.
科学领域:
- 心血管医学 心血管医学
- 老年病的医生 老年病的医生
- 血管健康 血管健康
背景情况:
- 周围动脉疾病 (PAD) 是心血管事件的重要危险因素.
- 脚和手臂血压指数 (AAI) 是一种用于评估PAD的非侵入性测量方法.
- 在老年人中,缩性高血压是一种普遍的疾病,与心血管风险增加有关.
研究的目的:
- 调查低脚/手臂血压指数 (AAI) 与短期心血管发病率和死亡率之间的关联.
- 为了确定AAI是否是心血管不良结果的预测因子,在患有静脉压高的老年人中.
主要方法:
- 前性队列研究,随访期为1至2年.
- 包括1,537名被诊断患有静缩高血压的老年男性和女性.
- 测量脚/手臂血压指数 (AAI) 和评估所有原因死亡率,冠心病 (CHD) 死亡率和心血管疾病 (CVD) 发病率和死亡率.
主要成果:
- 在25.5%的参与者中观察到低AAI (≤0.9),并与主要心血管风险因素相关.
- 低AAI的个体对总死亡率 (3.8),心脏病死亡率 (3.24) 和心脏病死亡率 (3.7) 的年龄和性别调整相对风险明显较高.
- 在对基线心血管疾病和风险因素进行调整后,低AAI仍然是总死亡率 (4.1) 和心血管疾病发病率/死亡率 (2.4) 的重要预测指标.
结论:
- 低脚/手臂血压指数 (AAI) 是患有静缩高血压的老年人发病率和死亡率的重要独立预测指标.
- AAI是高血压老年人群风险分层的一个有价值的工具.
- 早期识别低AAI可能有助于及时进行干预,以减少心血管事件.
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