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相关实验视频

一种淋巴毒素β特异性受体.

P D Crowe1, T L VanArsdale, B N Walter

  • 1Division of Biomedical Sciences, University of California, Riverside 92521.

Science (New York, N.Y.)
|April 29, 1994
PubMed
概括
此摘要是机器生成的。

瘤亡因子 (TNF) 和淋巴毒素α (LT-α) 是主要的免疫调节剂. 一个新发现的LT-β受体表明,与分泌的LT-α相比,细胞表面的LT具有不同的功能.

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科学领域:

  • 免疫学 免疫学 免疫学
  • 分子生物学分子生物学
  • 细胞生物学 细胞生物学

背景情况:

  • 瘤亡因子 (TNF) 和淋巴毒素α (LT-α) 是关键的细胞因子,参与免疫和炎症反应.
  • LT-α存在于分泌形式 (同分离体) 和细胞表面形式 (异构体复合体与LT-β).
  • 分泌的LT-alpha与60/80kDa的TNF受体结合,这些受体不识别细胞表面的LT-alpha-LT-beta复合体.