在大动脉狭窄症中恢复压力
1Cardiac Catheterization Laboratory, Hospital of the University of Pennsylvania, Philadelphia 19104.
Circulation
|January 1, 1994
概括
压力恢复,阻塞后血压的升高,在大动脉狭窄时是可变的. 它的程度取决于血液流动和膜区域,影响血液动力学评估.
科学领域:
- 心血管生理学心血管生理学
- 血液动力学 血液动力学
- 膜心脏疾病 膜心脏疾病
背景情况:
- 压力恢复被定义为侧向压力的增加,距离静脉孔的侧向压力.
- 在大动脉狭窄症中压力恢复的临床意义和程度尚不清楚.
研究的目的:
- 研究大动脉狭窄症患者的压力恢复的特征和决定因素.
- 评估压力恢复对血液动力学评估的临床影响.
主要方法:
- 高准确度的压力和速度记录在11名患者中获得,这些患者在心脏导管注射过程中单独出现了显著的大动脉狭窄.
- 导管拉回技术被用来测量压力梯度,并评估压力变化在狭窄性大动脉和上升性大动脉.
主要成果:
- 观察到一个一致的,虽然可变的,亚膜梯度.
- 压力恢复,即上升大动脉压力的增加,发生在静脉的远端,与脉冲波幅度的下降相关.
- 压力恢复的程度与全身和跨膜血流直接成比例,与使用戈林公式计算的大动脉面积相反.
结论:
- 压力恢复对轻度至中度大动脉狭窄的血液动力学评估具有重要意义.
- 在不同的生理条件下,量化压力恢复可能会提高对主动脉狭窄症严重性的评估.
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