非风湿性心房动的心声学预测因素. 弗雷明汉心脏研究
S M Vaziri1, M G Larson, E J Benjamin
1Framingham Heart Study, Mass 01701.
Circulation
|February 1, 1994
概括
左心房扩大和左心室壁厚度增加等心声预测因素可以识别患非风湿性心房动 (AF) 的风险较高的老年人. 这些发现提供了超越传统风险因素的宝贵预后见解.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 老年病的医生 老年病的医生
背景情况:
- 非风湿性心房动 (AF) 经常与结构性心脏病有关.
- 之前没有报告过AF的心声学前体.
- 这项研究调查了老年人群中的心声回声学预测因素.
研究的目的:
- 为了在老年人队伍中前性地确定非风湿性心房动的心声图预测因素.
- 评估AF风险的心声回声学发现的预后价值.
主要方法:
- 利用了1924年弗雷明汉心脏研究参与者 (年龄为59-90岁) 的M模式回声心脏学数据.
- 采用Cox的比例危险建模来分析心声学特征和AF风险之间的关联.
- 根据传统的风险因素进行调整,包括年龄,性别,高血压和心脏病.
主要成果:
- 在7.2年的随访期间,154名受试者患上了AF.
- 确定了独立的心声回声学预测因子:左心房大小,左心室分数缩短和隔膜/后壁结合厚度.
- 随着风险更高的心声回声学测量,AF的风险逐渐增加,特别是当结合时.
结论:
- 左心房扩大,左心室壁厚度增加和左心室部分缩短减少预测老年人非风湿性AF风险.
- 这些心声回声学标记提供了超出已确定的临床风险因素的预后信息.
- 心声图可以帮助识别AF风险较高的个体.
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