症状,不良反应和并发症与dobutamine压力心声学相关. 在1118名患者的经验
1Krannert Institute of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis.
Circulation
|July 1, 1993
概括
多布胺应激回声心电图是评估冠状动脉疾病的安全和有效工具,即使在复杂的患者中也是如此. 这项研究没有发现严重的并发症,在手术过程中出现了轻微的副作用和耐受良好的心律失常.
科学领域:
- 心脏病学 心脏病学
- 诊断成像 诊断成像 诊断成像
- 临床医学 临床医学
背景情况:
- 多布胺应激心声学 (DSE) 越来越多地用于冠状动脉疾病 (CAD) 评估.
- 它的安全性,特别是在晚期CAD患者中,需要进一步的文档.
研究的目的:
- 在大量患者队列中评估DSE的安全性和耐受性.
- 评估与DSE相关的并发症和副作用的发生率.
主要方法:
- 一系列1118名患者接受了已知或疑似CAD的DSE.
- 采用了多布胺 (高达50毫克克/公斤/分钟) 和氨酸的积极剂量方案.
- 患者被监测不良事件,心律失常和缺血症状.
主要成果:
- 没有死亡,心肌梗塞或持续的腹腔动脉冲动发生.
- 在3%的患者中报告了轻微的非心脏性副作用 (恶心,头痛).
- 胸痛发生在19.3%的人群中,有效地使用舌下酸甘或β-阻断剂进行管理.
- 节律失常,包括早发性心室综合体和非持续性心室低心率,一般都能很好地忍受.
结论:
- 通过积极的剂量方案和补充阿特罗宾,可以安全地进行DSE.
- 该程序耐受良好,具有轻微的副作用和可控的心律失常.
- 本研究中没有观察到与心肌缺血相关的严重并发症.
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