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Updated: Aug 20, 2026

Avidity-based Extracellular Interaction Screening (AVEXIS) for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions
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Avidity-based Extracellular Interaction Screening (AVEXIS) for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions

Published on: March 5, 2012

信号序列陷:对于分泌蛋白和I型膜蛋白的克隆策略

K Tashiro1, H Tada, R Heilker

  • 1Department of Medical Chemistry, Kyoto University Faculty of Medicine, Japan.

Science (New York, N.Y.)
|July 30, 1993
PubMed
概括

研究人员开发了一种新的方法来克隆编码信号序列的互补DNA (cDNA),而无需功能测试. 这项技术成功地鉴定出了两种新型细胞因子分子,即来自骨髓骨髓细胞系的肌肉细胞衍生因子-1α (SDF-1α) 和SDF-1β.

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