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Updated: May 17, 2026

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates
11:28

Affinity Precipitation of Active Rho-GEFs Using a GST-tagged Mutant Rho Protein (GST-RhoA(G17A)) from Epithelial Cell Lysates

Published on: March 31, 2012

在Ras上,Grb2调解了依赖于EGF的关氨酸核酸交换的激活

N W Gale1, S Kaplan, E J Lowenstein

  • 1Cold Spring Harbor Laboratory, New York 11724.

Nature
|May 6, 1993
PubMed
概括

Grb2蛋白通过增加Ras激活来增强表皮生长因子受体 (EGFR) 信号传递. 这种蛋白质复合体的形成将EGFR与Ras联系起来,调节细胞生长途径.

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