免疫毒素治疗癌症的治疗方法

Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.

The Journal of biological chemistry·1992

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

The Journal of biological chemistry·1992

Transfer and expression of the human multidrug resistance gene in mouse erythroleukemia cells.

Blood·1992

Alanine scanning mutagenesis identifies surface amino acids on domain II of Pseudomonas exotoxin required for cytotoxicity, proper folding, and secretion into periplasm.

The Journal of biological chemistry·1992

Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.

Blood·1992

Transfer and expression of the human multiple drug resistance gene into live mice.

Proceedings of the National Academy of Sciences of the United States of America·1992

Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.

JAMA·2026

Ceperognastat in Early Symptomatic Alzheimer Disease: A Randomized Clinical Trial.

JAMA·2026

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

JAMA·2026

Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease.

JAMA·2026

YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer: A Randomized Clinical Trial.

JAMA·2026

Tertiary lymphoid structures as biomarkers and therapeutic targets in neoadjuvant cancer immunotherapy.

Frontiers in immunology·2026

The hidden tumour: giant anterior mediastinal thymolipoma, an incidental finding.

Polish journal of pathology : official journal of the Polish Society of Pathologists·2026

FADS1-mediated Efferocytosis in Tumor-Associated Macrophages Shapes an Immunosuppressive Microenvironment in Gastric Cancer.

Cellular and molecular life sciences : CMLS·2026

The tumoural landscape of lymphocytes and immune pathways in immunotherapy-treated melanoma patients.

Genes and immunity·2026

Strategic engineering B cell immunity for cancer immunotherapy.

Journal of controlled release : official journal of the Controlled Release Society·2026

An Endometrioid Carcinoma With an Adenoma Malignum-like Pattern of Invasion: New Insight into Molecular Features.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists·2026

相关实验视频

免疫毒素治疗癌症的治疗方法

相关概念视频

Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol.

Identification of residues in the first cytoplasmic loop of P-glycoprotein involved in the function of chimeric human MDR1-MDR2 transporters.

Transfer and expression of the human multidrug resistance gene in mouse erythroleukemia cells.

Alanine scanning mutagenesis identifies surface amino acids on domain II of Pseudomonas exotoxin required for cytotoxicity, proper folding, and secretion into periplasm.

Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.

Transfer and expression of the human multiple drug resistance gene into live mice.

Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.

Ceperognastat in Early Symptomatic Alzheimer Disease: A Randomized Clinical Trial.

Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.

Clinicopathologic Evaluation of Amyloid Clearance in Alzheimer Disease.

YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer: A Randomized Clinical Trial.

Tertiary lymphoid structures as biomarkers and therapeutic targets in neoadjuvant cancer immunotherapy.

The hidden tumour: giant anterior mediastinal thymolipoma, an incidental finding.

FADS1-mediated Efferocytosis in Tumor-Associated Macrophages Shapes an Immunosuppressive Microenvironment in Gastric Cancer.

The tumoural landscape of lymphocytes and immune pathways in immunotherapy-treated melanoma patients.

Strategic engineering B cell immunity for cancer immunotherapy.

An Endometrioid Carcinoma With an Adenoma Malignum-like Pattern of Invasion: New Insight into Molecular Features.

相关实验视频

免疫毒素治疗癌症的治疗方法

相关概念视频

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