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Updated: May 3, 2026

Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC Crosslinking of Small Molecules to Isolate Chromatin
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高亲和度DNA结合的Myc类似物:通过α螺旋体的识别

D E Fisher1, L A Parent, P A Sharp

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.

Cell
|February 12, 1993
PubMed
概括

研究人员在基本螺旋环-螺旋-氨酸拉链 (b-HLH-ZIP) 蛋白中确定了关键氨基酸,这些蛋白质对于DNA结合至关重要. 突变性研究揭示了增强对CACGTG序列的DNA结合亲和力的策略.

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