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Updated: Aug 14, 2026

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP
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Published on: October 17, 2015

阿尔茨海默氏症粉样蛋白前体复合物与大脑GTP结合蛋白G (o)

I Nishimoto1, T Okamoto, Y Matsuura

  • 1Fourth Department of Internal Medicine, University of Tokyo School of Medicine, Japan.

Nature
|March 4, 1993
PubMed
概括

阿尔茨海默病涉及粉样前体蛋白 (APP) 的变化. 这项研究揭示了APP作为受体,与G(o) 蛋白形成复合体,表明异常的APP-G(o) 信号有助于阿尔茨海默病的发病.

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